THABO Ntsibande's family needs help to find him.
The 26-year-old from Vosloorus in Ekurhuleni went missing on 6 November.
Thabo's sister Sibongile Ntsibane (36) said Thabo's life changed in 2016 when he was affected by the death of his father Duze Kunene.
Sibongile said she and Thabo, who's mentally challenged, have different fathers.
"Thabo always stayed indoors at home. But on the day he went missing, he acted strangely.
"He was given food by our mother, but he pushed her away and left the house," said Sibongile.
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Sibongile said the family has been looking for him everywhere, including hospitals.
"We have put his photos on Facebook and in different places in and around Vosloorus," she said.
"Our wish is for him to return home safely," she said.
She said her brother's disappearance has affected everyone in the family.
"My daughter Wanele Ntsibande (10) has been asking us when her uncle will be back at home.
Police spokeswoman Captain Neldah confirmed a missing person's case has been opened at the Vosloorus cop shop.
Sibongile said anyone with information on the whereabouts of Thabo can contact her at 072 910 6966 or 072 303 3345.