Two earners from Noordeland High School in Polokwane were stabbed.
They were reportedly also injected with an unknown substance by the unknown suspects.
The police were called to the scene at the corner of General Maritz and General Delaray streets at Welgelegen, Bendor.
Police spokesperson Brigadier Motlafela Mojapelo said on arrival, the police found the two victims, one 13-year-old and another aged 14-years-old, being treated by emergency medical personnel.
They were then taken to the hospital where they were admitted.
“The police in Polokwane have opened a case of Assault GBH after two children aged 14 and 13 were allegedly stabbed and injected with unknown substance,” Mojapelo said.
Mojapelo further said the circumstance that led to the incident are unknown at this stage and anyone with information can contact the nearest police or the Crime Stop number 08600 10111.
